What is Biotin?
Biotin goes by several other names: vitamin H, vitamin B7, and coenzyme R. Biotin is an essential molecule to biological processes which cannot be produced in the body. Like all vitamins, it must be ingested in the diet. Currently, high dose biotin at a dose of 300 mg every day is being clinically investigated for the improvement of symptoms in progressive forms of multiple sclerosis (MS). This dose is 10,000 times higher than the adequate daily intake recommendations. Current disease-modifying therapies are used only to delay progression of primary progressive multiple sclerosis (PPMS) and secondary progressive multiple sclerosis (SPMS) or for active progressive disease. There is currently no disease-modifying therapy for patients with non-active progressive MS. Preliminary evidence has suggested biotin may be able to improve symptoms in PPMS and SPMS while being well tolerated. Still, these results are in their infancy and high dose biotin is not yet approved for this indication.
How Dose it Work?
Biotin is a cofactor for four essential enzymes in the human body which help the body build fatty acids from smaller molecular building blocks. Without biotin these enzymes cannot function. The destruction of the fatty myelin sheath surrounding nerves is thought to be the underlying pathology of MS. It is theorized that supplying large amounts of biotin helps these enzymes function to recreate the myelin sheath thereby increasing overall function for the patient.
The recommended dose is 100mg three times a day.
100mg Biotin is available from us over the counter without a prescription however we recommend that you discuss the suitability of this treatment with your doctor before starting it.
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